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Circadian regulation of feeding in rats: suprachiasmatic versus ventromedial hypothalamic nuclei
1Department of Physiology, Medical Academy, Sofia, Bulgaria.
Abstract:
The role of the suprachiasmatic nuclei as a major component of a specific circadian system controlling feeding periodicity is reviewed. Evidence is presented supporting the assumption that the ventromedial hypothalamus and the suprachiasmatic nucleus may act as a constant (tonic) regulator and a circadian modulator respectively of feeding in rats. It is concluded that a specific circadian system differing from the metabolic control mechanism superimposes the circadian periodicity of feeding. A model is put forward for the possible functional relationships between circadian and metabolic (homeostatic) control mechanisms of feeding in rats.
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