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Using nano-selenium to combat Coronavirus Disease 2019 (COVID-19)?
Lina He1,2, Jiating Zhao1, Liming Wang1
1CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, & CAS-HKU Joint Laboratory of Metallomics on Health and Environment, & Beijing Metallomics Facility, & National Consortium for Excellence in Metallomics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
Selenium (Se) is vital for antioxidant and immune support, showing antiviral effects. This review explores selenium
Area of Science:
- Nutritional Science
- Immunology
- Virology
Background:
- The COVID-19 pandemic is a significant global health crisis.
- Selenium (Se) is an essential trace element with known antioxidant and immune-boosting properties.
- These properties suggest a potential antiviral effect.
Purpose of the Study:
- To review the current understanding of selenium's role in combating viral infections.
- To explore the potential of nano-selenium (nanoSe) as a therapeutic strategy against COVID-19.
Main Methods:
- Literature review of existing studies on selenium and viral infections.
- Analysis of research on nano-selenium's properties and applications.
- Synthesis of current evidence regarding selenium's impact on viral pathogenesis.
Main Results:
- Selenium demonstrates significant antioxidant and immunomodulatory effects beneficial for antiviral defense.
- Evidence suggests selenium's potential to mitigate viral replication and disease severity.
- Nano-selenium exhibits enhanced bioavailability and antiviral activity compared to conventional selenium.
Conclusions:
- Selenium plays a crucial role in supporting the immune system against viral threats.
- Nano-selenium presents a promising avenue for novel therapeutic interventions against COVID-19.
- Further research into nano-selenium for COVID-19 treatment is warranted.
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