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Updated: Nov 28, 2025
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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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Bilateral Botryoid Wilms Tumor presented with acute renal failure
Gholamreza Bahoush1, Rozhin Pahlavani2, Sareh Salarinejad3
1Ali-Asghar Children Hospital, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Radiology Case Reports
|November 30, 2020
Summary
This case study highlights a rare bilateral botryoid Wilms tumor in a young boy, successfully treated with chemotherapy and nephron-sparing surgery. The patient showed no recurrence after 15 months, demonstrating effective treatment for this uncommon kidney cancer presentation.
Area of Science:
- Pediatric Oncology
- Urologic Oncology
- Nephropathology
Background:
- Botryoid Wilms tumor is a rare variant of Wilms tumor, characterized by intrapelvic polypoid masses.
- Bilateral involvement is exceptionally uncommon, posing unique diagnostic and therapeutic challenges.
Observation:
- A 19-month-old boy presented with acute renal failure due to hydronephrosis.
- Imaging revealed bilateral botryoid Wilms tumors with ureteral extension causing the obstruction.
Findings:
- The patient underwent successful treatment involving chemotherapy and bilateral nephron-sparing surgery in two separate procedures.
- A 15-month follow-up revealed no evidence of tumor recurrence or metastasis.
Implications:
- This case underscores the feasibility of nephron-sparing surgery for bilateral botryoid Wilms tumors.
- Successful management highlights the importance of multimodal therapy in rare pediatric renal malignancies.
- Early diagnosis and prompt intervention are crucial for favorable outcomes in complex Wilms tumor cases.
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