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Updated: Nov 28, 2025

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Impact of the COVID-19-pandemic on thrombectomy services in Germany
Steffen Tiedt1,2, Felix J Bode3,4, Timo Uphaus5
1Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany.
Insights
The COVID-19 pandemic did not significantly impact emergency workflows or patient outcomes for large-vessel occlusion (LVO) stroke treated with endovascular thrombectomy (ET) in Germany. Treatment efficacy and functional outcomes remained consistent compared to pre-pandemic periods.
Area of Science:
- Neurology
- Emergency Medicine
- Public Health
Background:
- The COVID-19 pandemic potentially disrupted established emergency workflows for large-vessel occlusion (LVO) stroke.
- Optimizing patient outcomes in LVO stroke relies on efficient emergency care pathways.
Purpose of the Study:
- To analyze workflow time intervals and functional outcomes for LVO patients undergoing endovascular thrombectomy (ET) during the COVID-19 pandemic in Germany.
- To assess the impact of the pandemic on the efficiency and effectiveness of stroke care.
Main Methods:
- A comparative study of LVO patients treated with ET between March 1st and May 31st, 2020, and the same period in 2019.
- Analysis included workflow times, reperfusion rates, and functional outcomes across 12 German hospitals.
- A total of 795 patients were included in the analysis.
Main Results:
- The number of LVO patients treated with ET remained similar between 2020 and 2019.
- Pre- and intrahospital workflow times were comparable, with a noted exception of longer door-to-groin times for interhospital transfer patients in 2020.
- Reperfusion rates and functional outcomes at discharge were not significantly different between the two periods.
Conclusions:
- Pre- and intrahospital workflows for LVO stroke patients treated with ET were not adversely affected by the COVID-19 pandemic.
- The efficacy of endovascular thrombectomy and the functional outcomes for LVO patients remained stable during the pandemic.
- This large cohort study from German centers indicates resilience in stroke care pathways during the pandemic.
Background:
The Coronavirus Disease 2019 (COVID-19) pandemic may have altered emergency workflows established to optimize the outcome of patients with large-vessel occlusion (LVO) stroke.
Aims:
We here analyzed workflow time intervals and functional outcomes of LVO patients treated with endovascular thrombectomy (ET) during the COVID-19 pandemic in Germany.
Methods:
We compared the frequency, pre- and intrahospital workflow time intervals, rates of reperfusion, and functional outcome of patients admitted from March 1st to May 31st 2020 with patients admitted during the same time interval in 2019 to 12 university and municipal hospitals across Germany (N = 795).
Results:
The number of LVO patients treated with ET between March to May 2020 was similar when compared to the same interval in 2019. Direct-to-center patients and patients admitted through interhospital transfer in 2020 showed similar pre- and intrahospital workflow time intervals compared to patients admitted in 2019, except for a longer door-to-groin time in patients admitted through interhospital transfer in 2020 (47 min vs 38 min, p = 0.005). Rates of reperfusion were not significantly different between 2020 and 2019. Functional outcome at discharge of LVO patients treated in 2020 was not significantly different compared to patients treated in 2019.
Conclusion:
Pre- and intrahospital workflows, ET efficacy, and functional outcome of LVO patients treated with ET were not affected during the COVID-19 pandemic in our large cohort from centers across Germany.
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