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Updated: Nov 28, 2025

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
Published on: January 7, 2021
Fetal cardiovascular magnetic resonance imaging
Julien Aguet1,2, Mike Seed1,2,3, Davide Marini4
1Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Fetal cardiovascular magnetic resonance imaging (MRI) offers a promising tool for diagnosing congenital heart disease when ultrasound is unclear. Ongoing advancements are improving its clinical use for prenatal diagnosis and management.
Area of Science:
- Medical imaging
- Cardiology
- Pediatrics
Background:
- Congenital heart disease (CHD) diagnosis often relies on ultrasound.
- Quantitative cardiovascular data can be crucial for CHD management.
- Fetal cardiovascular MRI presents a developing diagnostic modality.
Purpose of the Study:
- To review the current state of fetal cardiovascular MRI.
- To summarize clinical applications of this technique.
- To highlight ongoing technical advancements.
Main Methods:
- Review of existing literature on fetal cardiovascular MRI.
- Analysis of technical capabilities and limitations.
- Summary of clinical use cases in prenatal CHD.
Main Results:
- Fetal cardiovascular MRI is valuable when ultrasound is inconclusive for CHD.
- It provides essential quantitative data on blood flow, oxygen saturation, and hematocrit.
- Technical limitations exist but are being addressed by ongoing advances.
Conclusions:
- Fetal cardiovascular MRI is a promising diagnostic tool for CHD.
- It complements ultrasound by offering quantitative insights.
- Continued technical progress enhances its clinical utility and robustness.
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