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Transgenic Plants

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...

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Related Experiment Video

Updated: Nov 28, 2025

Microinjection of Western Corn Rootworm, Diabrotica virgifera virgifera, Embryos for Germline Transformation, or CRISPR/Cas9 Genome Editing

Microinjection of Western Corn Rootworm, Diabrotica virgifera virgifera, Embryos for Germline Transformation, or CRISPR/Cas9 Genome Editing

Published on: April 27, 2018

A new Bacillus thuringiensis protein for Western corn rootworm control.

Yong Yin¹, Stanislaw Flasinski¹, William Moar¹

¹Bayer Crop Science, Chesterfield, Missouri, United States of America.

|November 30, 2020

Summary

A new insecticidal protein, Vpb4Da2, effectively controls Western corn rootworm (WCR) resistant to current Bt maize. This discovery offers a vital new tool for WCR management in agriculture.

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Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells

Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells

Published on: August 20, 2018

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Last Updated: Nov 28, 2025

Microinjection of Western Corn Rootworm, Diabrotica virgifera virgifera, Embryos for Germline Transformation, or CRISPR/Cas9 Genome Editing

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Published on: April 27, 2018

Using Flight Mills to Measure Flight Propensity and Performance of Western Corn Rootworm, Diabrotica virgifera virgifera LeConte

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Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells

Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells

Published on: August 20, 2018

Area of Science:

Agricultural Entomology
Molecular Biology
Pest Management

Background:

Western corn rootworm (WCR) is a major North American agricultural pest.
Current control methods, including Bacillus thuringiensis (Bt) maize, face challenges due to emerging pest resistance.
There is a critical need for novel WCR control strategies.

Purpose of the Study:

To discover and characterize new insecticidal proteins effective against WCR.
To evaluate the efficacy of a novel protein, Vpb4Da2, against WCR in transgenic maize.

Main Methods:

High-throughput genome sequencing of a Bacillus thuringiensis strain.
Identification and characterization of the Vpb4Da2 insecticidal protein.
Field trials of transgenic maize expressing Vpb4Da2 against WCR.

Main Results:

Discovery of Vpb4Da2, a novel insecticidal protein with a distinct sequence and domain signature.
Transgenic maize expressing Vpb4Da2 provided commercial-level root protection (NIS ≤ 0.25) against WCR.
Vpb4Da2 demonstrated efficacy against WCR populations resistant to other transgenic maize traits (Bt and RNAi).

Conclusions:

Vpb4Da2 is a potent new tool for controlling WCR.
This protein offers a viable solution for managing WCR populations resistant to existing control methods.
Vpb4Da2 represents a significant advancement in maize pest management.