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Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

332
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
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Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

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Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
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Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Atherosclerosis III: Management01:26

Atherosclerosis III: Management

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Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
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Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

261
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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Related Experiment Video

Updated: Nov 28, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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[Progress in obstructive sleep apnea and atherosclerosis].

Haili Sun, Yanwen Qin, Yongxiang Wei

    Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
    |November 30, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Obstructive sleep apnea (OSA) is linked to atherosclerosis, but research findings are inconsistent. More basic and clinical studies are needed to understand the connection between OSA and atherosclerosis development.

    Keywords:
    atherosclerosisendothelial functionintermittent hypoxiasleep apnea, obstructive

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    Area of Science:

    • Cardiovascular Science
    • Sleep Medicine
    • Pathophysiology

    Background:

    • Obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by pharyngeal narrowing, leading to intermittent hypoxia, sleep disruption, and daytime sleepiness.
    • OSA is implicated in the development of atherosclerosis via direct and indirect pathways.
    • Existing research indicates a correlation between OSA and atherosclerosis, yet results remain inconsistent.

    Purpose of the Study:

    • To review the current understanding of the relationship between obstructive sleep apnea and atherosclerosis.
    • To highlight the need for further investigation into the underlying mechanisms connecting OSA and atherosclerosis.

    Main Methods:

    • Review of animal and clinical studies examining the link between OSA and atherosclerosis.
    • Analysis of existing literature on the risk factors associated with OSA and cardiovascular disease.

    Main Results:

    • Evidence suggests a significant association between OSA and atherosclerosis.
    • Inconsistent findings in current studies necessitate further research.
    • Direct and indirect mechanisms linking OSA to atherosclerosis require elucidation.

    Conclusions:

    • A clear relationship exists between obstructive sleep apnea and atherosclerosis.
    • Further basic and clinical research is essential to fully understand the complex interplay between OSA and the development of atherosclerosis.
    • Investigating the precise mechanisms is crucial for future therapeutic strategies.