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Studying the mixture effects of brominated flame retardants and metal ions by comet assay

Biyan Wang1, Haiyan Wang2, Daxiong Han3

  • 1School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China; Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, 361005, China.

Environmental Pollution (Barking, Essex : 1987)
|December 1, 2020
PubMed

Keywords:
BFRsComet assayDNA damageMetal ionsMixture

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Effects of EDTA on End-Point Detection Methods

Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...