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An integrated healthcare system (IHS) is a set of organizations that provides for or arranges to provide coordinated and continuous service to a defined population. The IHS takes responsibility for that particular population's health status and outcome, both clinically and fiscally. An integrated healthcare system is a well-organized, well-coordinated, and collaborative network. The integrated delivery system is a network that connects different healthcare providers to deliver organized,...
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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
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Isabl Platform, a digital biobank for processing multimodal patient data.

Juan S Medina-Martínez1,2, Juan E Arango-Ossa1, Max F Levine1

  • 1Memorial Sloan Kettering Cancer Center, New York, NY, USA.

BMC Bioinformatics
|December 1, 2020
PubMed
Summary
This summary is machine-generated.

Isabl is a new platform that makes it easy to process and analyze patient data. This digital biobank helps researchers by organizing data for better insights and discoveries.

Keywords:
Analysis information management systemData processingGenomicsImage processingMultimodal dataNext generation sequencingSoftware engineering

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Area of Science:

  • Biotechnology
  • Bioinformatics
  • Data Science

Background:

  • High-throughput technologies have increased data generation but lead to data silos.
  • Challenges exist in processing and managing large datasets according to best practices.
  • Digital biobanks offer a solution for accessible, structured, and annotated data.

Purpose of the Study:

  • To present Isabl, a customizable platform for processing multimodal patient-centric data.
  • To establish a digital biobank ecosystem for dynamic data querying and analysis.

Main Methods:

  • Isabl features a relational database (Isabl DB), command-line client (Isabl CLI), RESTful API (Isabl API), and web application (Isabl Web).
  • Automated deployment of validated pipelines across data assets.
  • Implementation of a full audit trail for data provenance, governance, and reproducibility.

Main Results:

  • Isabl provides a unified platform for multimodal patient data processing.
  • Automated pipeline deployment ensures efficient data management.
  • Comprehensive audit trails enhance data security and reproducibility.

Conclusions:

  • Isabl functions as a digital biobank, enabling continuous data utilization.
  • Facilitates automated meta-analyses at scale.
  • Acts as a catalyst for research innovation, discovery, and clinical translation.