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Updated: Nov 28, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Cardiogenic shock: incidence, survival and mechanical circulatory support usage 2007-2017-insights from a national
Corinna N Lang1,2, Klaus Kaier3, Viviane Zotzmann4,5
1Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany. corinna.nadine.lang@uniklinik-freiburg.de.
Insights
The incidence of cardiogenic shock (CS) is rising, yet survival rates remain low. Mechanical circulatory support (MCS) use in CS patients has decreased, with shifts in device types and varying survival outcomes.
Area of Science:
- Cardiology
- Intensive Care Medicine
- Medical Technology
Background:
- Cardiogenic shock (CS) management relies on mechanical circulatory support (MCS) to maintain cardiac output.
- Understanding the trends in MCS utilization and outcomes for CS is crucial for clinical practice.
Purpose of the Study:
- To quantify the incidence, outcomes, and influence of MCS in cardiogenic shock patients over a decade (2007-2017).
Main Methods:
- Retrospective analysis of CS patients hospitalized in a German tertiary university hospital from 2007-2017.
- Utilized ICD-10 code R57.0 for CS identification and German procedure codes (OPS) for MCS application.
Main Results:
- CS incidence increased by 65.6% from 2007 to 2017, with overall hospital survival remaining low (around 40%).
- MCS utilization in CS patients decreased from 16.0% in 2007 to 13.9% in 2017.
- Significant survival differences observed among MCS devices: Intra-aortic balloon pump (IABP) showed higher survival (49.5%) compared to percutaneous ventricular assist devices (pVAD) (36.2%) and extracorporeal membrane oxygenation (VA-ECMO) (30.5%).
Conclusions:
- Despite rising CS incidence, hospital survival rates are stagnant.
- MCS use in CS patients has declined, with evolving device preferences.
- Device-specific survival rates vary significantly, highlighting the need for careful selection of MCS in CS management.
Background:
A central element in the management of cardiogenic shock (CS) comprises mechanical circulatory support (MCS) systems to maintain cardiac output (CO). This study aims to quantify incidence, outcome and influence of MCS in CS over the last decade.
Methods:
All patients hospitalized with CS in a tertiary university hospital in Germany between 2007 and 2017 were identified utilizing the international coding system ICD-10 with code R57.0. Application of MCS was identified via German procedure classification codes (OPS).
Results:
383,983 cases of cardiogenic shock were reported from 2007 to 2017. Patients had a mean age of 71 years and 38.5% were female. The incidence of CS rose by 65.6% from 26,828 cases in 2007 (33.1 per 100,000 person-years, hospital survival 39.2%) to 44,425 cases in 2017 (53.7 per 100,000 person-years, survival 41.2%). In 2007, 16.0% of patients with CS received MCS (4.6 per 100,000 person-years, survival 46.6%), dropping to 13.9% in 2017 (6.6 per 100,000 person-years, survival 38.6%). Type of MCS changed over the years, with decreasing use of the intra-aortic balloon pump (IABP), an increase in extracorporeal membrane oxygenation (VA-ECMO) and percutaneous ventricular assist device (pVAD) usage. Significant differences regarding in-hospital survival were observed between the devices (survival: overall: 40.2%; medical treatment = 39.5%; IABP = 49.5%; pVAD = 36.2%; VA-ECMO = 30.5%; p < 0.001).
Conclusions:
The incidence of CS is increasing, but hospital survival remains low. MCS was used in a minority of patients, and the percentage of MCS usage in CS has decreased. The use rates of the competing devices change over time.
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