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Published on: June 29, 2019
Herbal medicines in functional dyspepsia-Untapped opportunities not without risks
Kok-Ann Gwee1, Gerald Holtmann2, Jan Tack3
1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and Gleneagles Hospital, Singapore City, Singapore.
Herbal medicine shows promise as an adjunctive treatment for functional dyspepsia, offering multi-target benefits. Rigorous scientific evaluation is crucial for its wider acceptance in clinical practice.
Area of Science:
- Gastroenterology
- Pharmacology
- Integrative Medicine
Background:
- Current functional dyspepsia treatments have limitations.
- Herbal medicine is being explored as a complementary therapy.
- Growing scientific and public interest necessitates a review.
Purpose of the Study:
- Evaluate the therapeutic potential of herbal medicines for functional dyspepsia.
- Identify challenges in adopting herbal medicines in mainstream treatment.
- Assess the safety and efficacy of herbal products.
Main Methods:
- Reviewed functional dyspepsia treatment landscape and scientific interest in herbal medicine.
- Assessed preclinical and clinical data for commercial herbal medicines.
- Critically evaluated challenges in herbal medicine adoption.
Main Results:
- Herbal medicines often combine multiple herbs with diverse pharmacological effects.
- Some products show efficacy and safety in rigorous clinical trials.
- Concerns include lack of assessment, toxicity, and standardization.
Conclusions:
- Herbal medicine is a viable future option for functional dyspepsia management.
- Potential to target multiple pathophysiological mechanisms simultaneously.
- Requires scientific rigor for wider adoption in treatment algorithms.
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