Atomically Precise Preorganization of Open Metal Sites on Gold Nanoclusters with High Catalytic Performance

Gold nanoclusters with surface open sites are crucial for practical applications in catalysis. We have developed a surface geometric mismatch strategy by using mixed ligands of different type of hindrance. When bulky phosphine Ph₃ P and planar dipyridyl amine (Hdpa) are simultaneously used, steric repulsion between the ligands will reduce the ligand coverage of gold clusters. A well-defined access granted gold nanocluster [Au₂₃ (Ph₃ P)₁₀ (dpa)₂ Cl](SO₃ CF₃ )₂ (Au₂₃ , dpa=dipyridylamido) has been successfully synthesized. Single crystal structural determination reveals that Au₂₃ has eight uncoordinated gold atoms in the shape of a distorted bicapped triangular prism. The accessibility of the exposed Au atoms has been confirmed quantitatively by luminescent titration with 2-naphthalenethiol. This cluster has excellent performance toward selective oxidation of benzyl alcohol to benzaldehyde and demonstrates excellent stability due to the protection of negatively charged multidentate ligand dpa.