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Pre-training phenotyping classifiers.

Dmitriy Dligach1, Majid Afshar2, Timothy Miller3

  • 1Loyola University Chicago, Department of Computer Science, Chicago, IL, United States.

Journal of Biomedical Informatics
|December 1, 2020
PubMed
Summary
This summary is machine-generated.

We developed a self-supervised pre-training method for transformer models that overcomes input length limitations in clinical text classification. This approach maintains most performance gains compared to supervised methods, even with slightly lower scores.

Keywords:
Automatic phenotypingNatural language processingPre-training

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Area of Science:

  • Natural Language Processing
  • Clinical Informatics
  • Machine Learning

Background:

  • Transformer-based pre-trained language models are standard for text classification.
  • Their clinical application is limited by input length constraints for encounter/patient-level tasks.

Purpose of the Study:

  • Introduce a self-supervised pre-training method for clinical text classification.
  • Address the input length limitation of transformer models.
  • Compare self-supervised with supervised pre-training methods.

Main Methods:

  • Developed a self-supervised pre-training approach using a masked token objective.
  • Pre-training method is free from maximum input length limitations.
  • Compared performance against supervised pre-training using billing codes.

Main Results:

  • Evaluated on four datasets (one public, three in-house) using AUC and F1 score.
  • Self-supervised pre-training performed slightly worse than supervised pre-training.
  • The proposed method retained a significant portion of the performance benefits from pre-training.

Conclusions:

  • Self-supervised pre-training is a viable alternative for clinical text classification.
  • The method effectively handles long clinical texts without input length restrictions.
  • It preserves substantial performance improvements, making it suitable for clinical applications.