Successful hematopoietic stem cell transplantation in a 4-1BB deficient patient with EBV-induced lymphoproliferation

Christine Wildermann1, Mohammed Alosaimi2, Sophie Liebenehm1

  • 1Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Germany.

Complete remission from recurrent EBV-positive lymphoma is not mandatory before HSCT to achieve long-term cure in a patient suffering from a recently described immunodeficiency affecting the T-cell coactivation molecule 4-1BB.