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Microstructured Devices for Optimized Microinjection and Imaging of Zebrafish Larvae
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Recent Advances in Microswimmers for Biomedical Applications.

Ada-Ioana Bunea1, Rafael Taboryski1

  • 1National Centre for Nano Fabrication and Characterization (DTU Nanolab), Technical University of Denmark, Ørsted Plads 347, 2800 Lyngby, Denmark.

Micromachines
|December 2, 2020
PubMed
Summary

Microswimmers show great promise for biomedical applications like drug delivery and microsurgery. While not yet clinically approved, research is advancing biocompatible designs for future medical use.

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Robotics

Background:

  • Microswimmers are microscopic devices capable of self-propulsion.
  • Their development has rapidly advanced over the past two decades.
  • Biomedical applications represent a significant area of interest due to their societal value.

Purpose of the Study:

  • To review recent advances in biomedical applications of microswimmers.
  • To summarize current research trends and potential uses.
  • To discuss challenges and considerations for clinical translation.

Main Methods:

  • Literature review of recent scientific publications.
  • Analysis of reported microswimmer designs and applications.
  • Synthesis of findings on biocompatibility and in vivo propulsion.
Keywords:
biomedical applicationdrug deliveryimagingmicrorobotmicroswimmersensing

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Last Updated: Nov 27, 2025

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Main Results:

  • Microswimmers are explored for cargo transport, drug delivery, artificial insemination, sensing, cell manipulation, imaging, and microsurgery.
  • Research focuses on developing biocompatible and biodegradable microswimmers.
  • In vivo-friendly propulsion methods are a key area of investigation.

Conclusions:

  • Microswimmer technology is progressing rapidly towards clinical applications.
  • Significant challenges remain in achieving clinical approval and commercialization.
  • Ongoing research is crucial for overcoming these hurdles and realizing the potential of microswimmers in medicine.