Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bacteroides fragilis meningitis.

H M Feder1

  • 1Department of Pediatrics, University of Connecticut Health Center, Farmington 06032.

Reviews of Infectious Diseases
|July 1, 1987
PubMed
Summary
This summary is machine-generated.

Bacteroides fragilis meningitis is rare, primarily affecting premature infants. Metronidazole shows effectiveness in treating this serious bacterial infection, though outcomes vary.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A clinical review of 105 patients with PFAPA (a periodic fever syndrome).

Acta paediatrica (Oslo, Norway : 1992)·2009
Same author

Management of tick bites and early Lyme disease: a survey of Connecticut physicians.

Pediatrics·2001
Same author

Zanamivir to prevent influenza.

The New England journal of medicine·2001
Same author

Tinea incognito misdiagnosed as erythema migrans.

The New England journal of medicine·2000
Same author

Methicillin-resistant Staphylococcus aureus infections in 2 pediatric outpatients.

Archives of family medicine·2000
Same author

Periodic fever, aphthous stomatitis, pharyngitis, adenitis: a clinical review of a new syndrome.

Current opinion in pediatrics·2000
Same journal

Fatal necrotizing otitis externa in a patient with AIDS.

Reviews of infectious diseases·1991
Same journal

Use of the polymerase chain reaction for the specific and direct detection of Clostridium difficile in human feces.

Reviews of infectious diseases·1991
Same journal

A new case of meningitis due to Pasteurella multocida.

Reviews of infectious diseases·1991
Same journal

Disseminated pelvic actinomycosis presenting as metastatic carcinoma: association with the progestasert intrauterine device.

Reviews of infectious diseases·1991
Same journal

Genetically engineered attenuated herpes simplex viruses.

Reviews of infectious diseases·1991
Same journal

Role of altered drug metabolism in virus-drug interactions.

Reviews of infectious diseases·1991
See all related articles

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Neonatal Care

Background:

  • Bacteroides fragilis, an anaerobic bacterium, is an uncommon pathogen in bacterial meningitis.
  • Meningitis cases caused by B. fragilis are infrequently reported, especially within the antibiotic era.

Observation:

  • Seven of the nine reported cases of B. fragilis meningitis occurred in premature infants and neonates.
  • Predisposing factors identified include abdominal sepsis, chronic otitis media, and ventriculoatrial shunt infections.

Findings:

  • Outcomes for B. fragilis meningitis patients were severe: two deaths, four survivors with neurologic sequelae, and three without sequelae.
  • Metronidazole, a bactericidal antibiotic, demonstrated the most effective therapeutic response.

Related Experiment Videos

Implications:

  • Highlights the importance of considering B. fragilis in neonatal meningitis, particularly with predisposing conditions.
  • Emphasizes metronidazole as a key treatment option for B. fragilis meningitis, guiding clinical management.
  • Underscores the significant morbidity and mortality associated with this rare but serious infection.