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Long-term Depression

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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Assessment and Communication for People with Disorders of Consciousness
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Publisher Correction: Delirium.

Jo Ellen Wilson1,2, Matthew F Mart3,4, Colm Cunningham5

  • 1Center for Critical Illness, Brain Dysfunction, and Survivorship (CIBS), Vanderbilt University Medical Center, Nashville, TN, USA. jo.e.wilson@vumc.org.

Nature Reviews. Disease Primers
|December 2, 2020
PubMed
Summary
This summary is machine-generated.

This study highlights the critical role of gut microbiota in modulating host immunity and metabolism. Alterations in gut bacteria composition are linked to various diseases, emphasizing the need for targeted microbiome interventions.

Area of Science:

  • Microbiology
  • Immunology
  • Metabolism

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