CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL

Anna Clara Rabha1, Francisco Ivanildo de Oliveira Junior1, Thales Araújo de Oliveira1

  • 1Instituto Pensi, Sabará Hospital Infantil, Fundação José Luiz Egydio Setúbal, São Paulo, SP, Brazil.

Insights

Most children with COVID-19 (Coronavirus Disease 2019) presented mild upper airway symptoms. Younger children experienced more severe illness, with increased gastrointestinal and respiratory symptoms, but no deaths were reported.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • COVID-19 (Coronavirus Disease 2019) significantly impacted global health, including pediatric populations.
  • Understanding the clinical spectrum in children is crucial for effective management and public health strategies.

Purpose of the Study:

  • To detail the clinical features and disease severity of pediatric COVID-19 patients treated at Sabará Hospital Infantil.
  • To identify risk factors associated with severe COVID-19 in children.

Main Methods:

  • A retrospective, observational, cross-sectional study analyzed 115 pediatric COVID-19 cases confirmed by RT-qPCR.
  • Patient data were collected from emergency, first-aid, and ICU settings.
  • Disease severity was assessed using the Chinese Consensus criteria.

Main Results:

  • The study included 115 children (57% boys, median age 2 years).
  • 22 children were hospitalized (12 in ICU), with younger children (median 7 months) being more likely to be hospitalized.
  • Fever, cough, and nasal discharge were common; 70% had upper respiratory symptoms, 14% severe pneumonia. No mechanical ventilation or deaths occurred.

Conclusions:

  • Pediatric COVID-19 predominantly presented as mild upper respiratory tract infections.
  • Younger children and those with comorbidities (e.g., asthma) showed more severe manifestations, including gastrointestinal and respiratory symptoms.
Abstract

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