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Cell-mediated immunity to Nocardia asteroides induced by its ribonucleic acid protein fraction
Infection and Immunity
|October 1, 1977
Abstract:
Guinea pigs immunized with ribonucleic acid protein fraction from Nocardia asteroides developed high cell-mediated immunity within 2 weeks, as shown by increased macrophage microbicidal activity and macrophage migration inhibition. This immunity protected against intravenous and subcutaneous challenge with N. asteroides and persisted for at least 70 days.