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Updated: Aug 7, 2026

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy
07:54

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy

Published on: December 15, 2011

NMR spectroscopy for clinical medicine. Animal models and clinical examples

M W Weiner1

  • 1Magnetic Resonance Unit, Veterans Administration Medical Center, San Francisco, California.

Annals of the New York Academy of Sciences
|January 1, 1987
PubMed

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Two-Dimensional (2D) NMR: Overview

The 1D NMR spectrum of large and complex molecules like natural products has complicated splitting patterns and overlapping signals, which can be easily interpreted using 2-dimensional (2D) NMR. Unlike 1D NMR, 2D NMR has two frequency axes that provide the coupling information between the nucleus A and nucleus B in a molecule. The process from which 2D spectra are obtained has four steps.
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NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

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