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How to Evaluate Patients for Tardive Dyskinesia
1Dauten Family Center for Bipolar Treatment Innovation, and the Depression Clinical and Research Program, Massachusetts General Hospital; and Department of Psychiatry, Harvard Medical School, Boston
The Journal of Clinical Psychiatry
|December 2, 2020
Summary
Tardive dyskinesia (TD) is a movement disorder affecting 20%-50% of patients on antipsychotics. Clinicians must systematically evaluate patients for TD due to its potential irreversibility and association with various medications.
Area of Science:
- Neurology
- Pharmacology
Background:
- Tardive dyskinesia (TD) is a significant adverse effect of antipsychotic medications, affecting 20%-50% of users.
- TD can also be associated with other drug classes like antidepressants, mood stabilizers, and stimulants.
- The prevalence of TD is increasing as more individuals are prescribed at-risk medications.
Purpose of the Study:
- To highlight the importance of systematic patient evaluation for tardive dyskinesia.
- To inform clinicians about the risks and associations of TD with various medications.
Main Methods:
- This study is a review of existing literature on tardive dyskinesia.
- It synthesizes information on the prevalence, associated drug classes, and clinical implications of TD.
Main Results:
- Antipsychotic drugs are the primary cause of TD, with a 20%-50% incidence rate.
- Numerous other medications, including antidepressants and stimulants, are also linked to TD development.
- TD poses a risk of being serious and potentially irreversible.
Conclusions:
- Healthcare providers need to be vigilant in assessing patients for TD.
- Systematic evaluation protocols are crucial for early detection and management of TD.
- Understanding the broad range of medications associated with TD is essential for patient safety.
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