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Updated: Nov 27, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Generalized granuloma annulare after pneumococcal vaccination
Miguel Fernando García-Gil1, Marcial Álvarez-Salafranca1, Alejandro Martínez García2
1Department of Dermatology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Abstract:
Granuloma annulare may be caused by multiple triggers. Among these are vaccinations, which have been described as an infrequent cause of granuloma annulare. The authors report the first case of generalized granuloma annulare associated with pneumococcal vaccination in a 57-year-old woman, who presented cutaneous lesions 12 days after vaccination.
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