Related Experiment Video
Updated: Nov 27, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Prostate MRI: practical guidelines for interpreting and reporting according to PI-RADS version 2.1
R Sánchez-Oro1, J Torres Nuez1, G Martínez-Sanz1
1Servicio de Radiodiagnóstico, Hospital General de Teruel Obispo Polanco, Teruel, España.
Multiparametric MRI (mpMRI) with PI-RADS 2.1 improves prostate cancer detection. This review details its interpretation for accurate diagnosis and management of significant prostate tumors.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Prostate cancer is the most common non-cutaneous cancer in men.
- Multiparametric MRI (mpMRI) has become crucial in prostate cancer management.
- Increasing precision and standardization enhance mpMRI's role.
Purpose of the Study:
- To review PI-RADS version 2.1 concepts for prostate cancer assessment.
- To provide practical guidance on mpMRI interpretation.
- To highlight common pitfalls and local spread evaluation.
Main Methods:
- Review of PI-RADS v2.1 guidelines.
- Practical approach to interpreting prostate mpMRI.
- Emphasis on prerequisites and findings interpretation.
- Criteria for assessing local spread probability.
Main Results:
- PI-RADS 2.1 standardizes the estimation of significant prostate tumor probability and location.
- Identifies benign findings that may mimic malignancy.
- Provides criteria for evaluating local spread potential.
- Highlights the importance of structured reporting.
Conclusions:
- Standardized mpMRI interpretation using PI-RADS 2.1 is essential for accurate prostate cancer management.
- Understanding potential diagnostic challenges improves clinical decision-making.
- Structured reporting of mpMRI findings facilitates optimal patient care.
Related Concept Videos
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Magnetic Resonance Imaging

