Related Experiment Video
Updated: Nov 27, 2025

07:13
Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
Published on: May 16, 2022
2.2K
Laser-driven x-ray and proton micro-source and application to simultaneous single-shot bi-modal radiographic imaging
T M Ostermayr1,2,3, C Kreuzer4, F S Englbrecht4
1Ludwig-Maximilians-Universität München, Fakultät für Physik, 85748, Garching, Germany. tmostermayr@lbl.gov.
Nature Communications
|December 3, 2020
Summary
Laser-driven plasma sources generate both proton and X-ray beams for simultaneous bi-modal radiographic imaging. This novel approach enables detailed imaging of biological and technological objects in a single shot.
Area of Science:
- Plasma Physics
- Radiographic Imaging
- Laser-Plasma Interactions
Background:
- Radiographic imaging using X-rays and protons is crucial in research and diagnostics.
- Simultaneously accessing information from both X-ray and proton radiography is challenging.
- Laser-driven plasma sources offer potential for generating both radiation types, but bi-modal applications are underdeveloped.
Purpose of the Study:
- To report the generation of proton and X-ray micro-sources using laser-plasma interactions.
- To demonstrate bi-modal radiographic imaging of objects in a single laser shot.
- To explore the advantages of laser-driven sources for advanced imaging.
Main Methods:
- Utilizing the Texas Petawatt laser focused on solid-density, micrometer-sized tungsten needles.
- Generating simultaneous proton and X-ray micro-sources through laser-plasma interactions.
- Applying the generated sources for bi-modal radiographic imaging of biological and technological samples.
Main Results:
- Successfully generated co-localized proton and X-ray micro-sources.
- Achieved bi-modal radiographic imaging of diverse objects in a single laser shot.
- Demonstrated the potential of laser-driven sources for simultaneous multi-modal imaging.
Conclusions:
- Laser-driven proton and X-ray micro-sources can be effectively generated for bi-modal imaging.
- This technique allows for simultaneous imaging of biological and technological samples.
- Laser-driven sources offer unique advantages like small footprint, spectral bandwidth, and multi-mode emission for advanced radiography.

