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Updated: Nov 27, 2025
05:14
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
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[Adherence to anti-VEGF treatment-Considerations and practical recommendations]
Albrecht Lommatzsch1, Nicole Eter2, Christoph Ehlken3
1Augenzentrum am St. Franziskus-Hospital, Münster, Deutschland.
Summary
Improving patient adherence to anti-VEGF injections is crucial for better visual outcomes. This study outlines strategies to reduce undertreatment by optimizing intravitreal injection schedules and patient communication.
Area of Science:
- Ophthalmology
- Retinal diseases
- Treatment adherence
Background:
- Lack of treatment adherence is a significant barrier to achieving optimal outcomes in anti-VEGF therapy.
- Infrequent or delayed intravitreal injections lead to undertreatment and suboptimal functional results.
Purpose of the Study:
- To discuss approaches and measures for reducing the risk of late and infrequent intravitreal injections.
- To address the issue of undertreatment by improving patient adherence to anti-VEGF therapy.
Main Methods:
- Expert dialogue to identify key parameters and variables related to treatment adherence.
- Structuring and assigning meaningful processes to relevant organizational areas.
- Identification of specific indicators affecting treatment adherence and visual function.
Main Results:
- Implementation of organizational measures, team training, and enhanced patient information transfer can improve adherence.
- Regular monitoring of treatment interruption and discontinuation is essential.
- Specific indicators like treatment delay and pause intervals demonstrate an effect on visual function development.
Conclusions:
- Process optimization can enhance adherence and functional outcomes in anti-VEGF therapy.
- Further interventional studies are needed to confirm methods for increasing adherence and persistence in the German treatment setting.
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