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Failure Modes in IROC Photon Liver Phantom Irradiations.
Paige A Taylor1, Paola E Alvarez1, Hunter Mehrens1
1IROC Houston Quality Assurance Center, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Practical Radiation Oncology
|December 3, 2020
Summary
Radiation therapy for liver phantom irradiations had a 27% failure rate, primarily due to localization errors. Improving motion management and target alignment is crucial for accurate patient treatment.
Area of Science:
- Medical Physics
- Radiation Oncology
Background:
- The Imaging and Radiation Oncology Core (IROC) utilizes anthropomorphic liver phantoms to simulate complex liver disease with respiratory motion.
- Accurate radiation delivery is critical for treating liver tumors, especially those with significant motion.
Purpose of the Study:
- To analyze and classify failure patterns in photon liver phantom irradiations.
- Identify common causes of irradiation failures in a simulated liver environment.
Main Methods:
- Analysis of 249 liver phantom irradiations conducted between 2013 and 2019.
- Categorization of failed irradiations by attributed error and comparison across machine type, planning system, motion management, and isocenter count.
Main Results:
- A 27% failure rate was observed in liver phantom irradiations.
- Localization errors in the direction of motion constituted over 50% of failures, followed by systematic dose errors.
- The internal target volume technique showed poorer performance compared to other motion management strategies.
Conclusions:
- Motion management techniques and precise alignment of moving targets are critical for successful liver phantom irradiation.
- Addressing localization and systematic dose errors is essential for improving patient treatment accuracy, particularly for liver disease and other sites with moving targets.

