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Updated: Nov 27, 2025

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

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Brain arteriovenous malformations.

Caleb Rutledge1, Daniel L Cooke2, Steven W Hetts2

  • 1Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, United States.

Handbook of Clinical Neurology
|December 4, 2020
PubMed
Summary
This summary is machine-generated.

Brain arteriovenous malformations (AVMs) can cause dangerous brain bleeds. Treatment for unruptured AVMs is debated due to risks, but aims for complete obliteration while preserving function.

Keywords:
Arteriovenous malformationEmbolizationIntracerebral hemorrhageMicrosurgeryRadiosurgery

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Area of Science:

  • Neurology
  • Neurosurgery
  • Vascular Medicine

Background:

  • Brain arteriovenous malformations (AVMs) are a significant cause of intracerebral hemorrhage, particularly in younger populations.
  • The high risk of rebleeding following rupture necessitates treatment for symptomatic AVMs.

Purpose of the Study:

  • To discuss the controversial management of incidentally discovered, unruptured brain arteriovenous malformations.
  • To outline the multimodal treatment options and the goal of preserving neurologic function.

Main Methods:

  • Review of current management strategies for brain AVMs.
  • Discussion of observation, microsurgical resection, endovascular embolization, and stereotactic radiosurgery.
  • Emphasis on multidisciplinary team evaluation for treatment decisions.

Main Results:

  • Treatment of ruptured AVMs is generally recommended due to high rebleeding risk.
  • Management of unruptured AVMs is controversial, balancing treatment risks against natural history.
  • Multimodal approaches are employed, requiring careful patient evaluation.

Conclusions:

  • Complete obliteration of brain AVMs is the primary treatment goal.
  • Preservation of neurologic function is paramount during AVM treatment.
  • Multidisciplinary collaboration is essential for optimal patient management.