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SERS based sensor for mycotoxins detection: Challenges and improvements.

Md Mehedi Hassan1, Muhammad Zareef1, Yi Xu1

  • 1School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China.

Food Chemistry
|December 4, 2020
PubMed
Summary
This summary is machine-generated.

Surface-enhanced Raman spectroscopy (SERS) offers sensitive detection of food contaminants. This study identifies key challenges in mycotoxin detection using SERS, proposing solutions for accurate food safety analysis.

Keywords:
Accuracy and precisionCross-reactivityMycotoxinsNon-specific adsorptionSelectivitySurface-enhanced Raman spectroscopy

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Area of Science:

  • Analytical Chemistry
  • Food Science
  • Spectroscopy

Background:

  • Surface-enhanced Raman spectroscopy (SERS) is a crucial ultrasensitive technique for quantifying toxic molecules in food.
  • Monitoring chemical contaminants ensures food security and guides production, processing, and risk assessment for consumer health.
  • Mycotoxin detection is vital for safeguarding food supplies.

Purpose of the Study:

  • To identify and discuss the challenges in detecting mycotoxins in foodstuffs using SERS.
  • To explore potential solutions for overcoming these analytical hurdles.

Main Methods:

  • Review and discussion of analytical parameters impacting SERS performance.
  • Analysis of challenges including selectivity, accuracy, precision, robustness, and ruggedness.
  • Examination of non-specific adsorption (NSA) and cross-reactivity issues.

Main Results:

  • Identified key challenges in SERS-based mycotoxin detection.
  • Discussed the impact of NSA and cross-reactivity on analytical results.
  • Highlighted the need for optimized affinity agents and nanomaterials.

Conclusions:

  • Addressing challenges like selectivity, accuracy, and NSA is crucial for reliable SERS mycotoxin quantification.
  • Development of specific affinity agents (antibodies, aptamers, MIPs) and surface modifications are key to improving SERS performance.
  • Overcoming these challenges will enhance food safety and consumer protection through advanced analytical methods.