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Updated: Nov 27, 2025

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Published on: December 17, 2014
Radiological aspects of CO2 peripheral DSA: Preliminary analysis on the dedicated protocols
Pier Luca Rossi1,2, David Bianchini3, Alessandro Lombi1,2
1O.U. Medical Physics, University of Bologna, Viale Berti Pichat 6/2, 40124 Bologna, Italy.
Objectives:
Thanks to its lack of allergic reactions and renal toxicity, CO2 represents an alternative to iodine as a contrast medium for peripheral subtraction angiography. Since CO2 has a lower and negative contrast than iodine, postprocessing DSA and stacking are mandatory. So, it seems that higher doses than traditional iodine angiography are required. We addressed the dosimetric aspects of CO2 angiography for two different commercial DSA-apparatus.
Materials And Methods:
Two different radiological suites were analyzed by recreating the same setup on all the apparatuses: we used a PMMA slabs phantom with a MPD Barracuda dosimeter on its side to collect all radiological parameters.
Results:
Results show that the irradiation parameters were left completely unchanged between the traditional and CO2 angiographic programs.
Conclusions:
This leads to thinking that these CO2 protocols do not operate on the X-ray emission, but only differ on image manipulation. The possibility of improvements by changing radiological parameters are still not explored and really promising.
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