Indirect immunofluorescence application in the epidemiological study of hepatitis A

We used IIF test for seroepidemiological study on 531 sera divided in age-groups obtained from apparently healthy subjects of Rome. Our results confirm the endemicity of HAV (Hepatitis A virus) infection in Rome with a prevalence of more than 50%. The application of the anti-HAV IIF (Indirect Immunofluorescence) test to a large number of sera demonstrated its usefulness as a quantitative and qualitative test in the epidemiological field.