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Sufentanil Sublingual Tablet System: from rationale of use to clinical practice
A Vergari1, A Cortegiani, M Rispoli
1Department of Anesthesiology, Intensive Care Medicine and Toxicology, A. Gemelli University Hospital Foundation, Catholic University of the Sacred Heart, Rome, Italy. alessandro.vergari@policlinicogemelli.it.
Abstract:
The control of post-operative pain in Italy and other western countries is still suboptimal. In recent years, the Sufentanil Sublingual Tablet System (SSTS; Zalviso; AcelRx Pharmaceuticals, Redwood City, CA, USA), which is designed for patient-controlled analgesia (PCA), has entered clinical practice. SSTS enables patients to manage moderate-to-severe acute pain during the first 72 postoperative hours directly in the hospital setting. However, the role of SSTS within the current framework of options for the management of post-operative pain needs to be better established. This paper presents the position on the use of SSTS of a multidisciplinary group of Italian Experts and provides protocols for the use of this device.
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