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Related Experiment Video

Updated: Nov 27, 2025

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
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Normal pressure hydrocephalus: Diagnostic delay.

Alejandra Saldarriaga-Cantillo1, Viviana Yepes-Gaviria2, Juan Carlos Rivas3

  • 1Escuela de Medicina, Universidad del Valle, Cali, Colombia. alejandrasaldarriaga20@yahoo.com.

Biomedica : Revista Del Instituto Nacional De Salud
|December 4, 2020
PubMed
Summary

This study examined how normal pressure hydrocephalus is diagnosed and treated in a psychiatric hospital in Colombia. Researchers looked at 35 patients who were suspected of having this condition and found that only five were considered suitable for a surgical shunt. Despite some short-term improvements after lumbar puncture, long-term benefits were not observed. The authors suggest that diagnostic protocols are not being followed consistently, leading to delays in treatment. This delay can have serious consequences for patients and their families, as the condition is potentially reversible with timely intervention.

Keywords:
Hydrocephalus/diagnosisnormal pressurespinal punctureageismdementiaprimary health carenormal pressure hydrocephalusdiagnostic delaylumbar puncturegeriatric psychiatryshunt placement

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Area of Science:

  • Neurological disorders diagnosis
  • Geriatric psychiatry
  • Cognitive impairment research

Background:

Normal pressure hydrocephalus remains a challenging condition to identify due to overlapping symptoms with other dementias. While prior research has highlighted its treatability, implementation of diagnostic protocols remains inconsistent. Patients often receive delayed evaluations, limiting early intervention opportunities. The condition's reversibility with surgical shunting contrasts with the irreversible nature of many neurodegenerative diseases. However, no prior work had resolved the extent of diagnostic delays in psychiatric settings. This gap motivated an investigation into diagnostic practices in a Colombian psychiatric hospital. The lack of standardized protocols for evaluating suspected cases has hindered timely treatment. Understanding these delays could inform better diagnostic approaches in similar clinical environments.

Purpose Of The Study:

The study aimed to examine the diagnostic process for normal pressure hydrocephalus in a psychiatric hospital setting. Researchers focused on identifying reasons for diagnostic and therapeutic delays in suspected cases. The specific problem addressed was the low rate of shunt placement despite available diagnostic tools. The motivation stemmed from the potentially reversible nature of the condition. The study sought to document clinical outcomes following lumbar puncture. It also aimed to assess the impact of delayed diagnosis on patient improvement. The goal was to highlight gaps in protocol implementation. The findings could guide improvements in diagnostic workflows for similar populations.

Main Methods:

The researchers conducted a retrospective analysis of medical records over five years. They identified patients with suspected normal pressure hydrocephalus for inclusion. Diagnostic lumbar punctures were performed on 35 participants. Five patients were considered candidates for peritoneal-venous shunt placement. No surgical procedures were completed for any of the candidates. Clinical outcomes were tracked for gait, cognition, and sphincter control. Follow-up assessments occurred three to six months after lumbar puncture. Long-term outcomes were evaluated at one year post-procedure.

Main Results:

Gait improvement occurred in 22.8% of patients after lumbar puncture. Cognition improved in the same proportion of participants. Sphincter control showed improvement in 11.4% of cases. These improvements were not sustained beyond one year in any patient. Only five patients were identified as suitable for shunt placement. None of the patients underwent the surgical procedure. The study highlights a gap in protocol implementation. The findings suggest significant delays in both diagnosis and treatment.

Conclusions:

The study emphasizes the underutilization of diagnostic protocols for normal pressure hydrocephalus. The authors propose that diagnostic delays limit treatment opportunities. They suggest that psychiatric settings may not prioritize neurological evaluations. The researchers highlight the importance of timely shunt placement. The findings indicate that current practices fail to identify eligible patients. The authors note that delayed diagnosis leads to poor long-term outcomes. They propose that better diagnostic workflows could improve patient care. The study underscores the need for improved protocol implementation.

The study found that 22.8% of patients showed gait improvement after lumbar puncture.

The study notes that none of the five identified candidates underwent shunt placement.

Improvements in gait and cognition lasted three to six months but were not sustained beyond one year.

Diagnostic lumbar puncture was used to assess suspected cases in the study.

Sphincter control improved in 11.4% of patients following lumbar puncture.

The authors suggest poor implementation of diagnostic protocols leads to treatment delays.