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Precision medicine for heart failure based on molecular mechanisms: The 2019 ISHR Research Achievement Award Lecture
Seitaro Nomura1, Issei Komuro1
1Department of Cardiovascular Medicine, The University of Tokyo, Japan.
Insights
Heart failure is a growing global health issue. Understanding its molecular basis is key to developing precision medicine approaches for cardiac hypertrophy and failure.
Area of Science:
- Cardiology and Molecular Medicine
Background:
- Heart failure represents a significant and increasing global health burden.
- Elucidating the molecular mechanisms of heart failure is crucial for advancing precision medicine.
Abstract:
Heart failure is a leading cause of death, and the number of patients with heart failure continues to increase worldwide. To realize precision medicine for heart failure, its underlying molecular mechanisms must be elucidated. In this review summarizing the "The Research Achievement Award Lecture" of the 2019 XXIII ISHR World Congress held in Beijing, China, we would like to introduce our approaches for investigating the molecular mechanisms of cardiac hypertrophy, development, and failure, as well as discuss future perspectives.
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