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Radiology of the lymphomas
1Department of Radiology, University of Utah School of Medicine, Salt Lake City.
Current Problems in Diagnostic Radiology
|July 1, 1987
Summary
Understanding lymphoma subtypes, including Hodgkin lymphoma (HD) and non-Hodgkin lymphoma (NHL), is crucial for effective imaging workups and staging. Radiologists must differentiate their distinct patterns of spread and histologic grades for accurate patient management.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Lymphomas present diagnostic challenges for radiologists and clinicians.
- Accurate histologic classification and staging are essential for effective patient management.
- Malignant lymphomas share radiographic features but exhibit key differences.
Purpose of the Study:
- To highlight the importance of understanding lymphoma histology and staging in imaging.
- To differentiate imaging approaches for Hodgkin lymphoma (HD) and non-Hodgkin lymphoma (NHL).
- To guide efficient staging workups and post-treatment follow-up strategies.
Main Methods:
- Review of radiographic features and patterns of extension for HD and NHL.
- Correlation of histologic classification (low, intermediate, high grade) with disease presentation.
- Analysis of imaging modalities for staging and follow-up based on lymphoma type.
Main Results:
- HD typically shows contiguous extension along lymphatic channels, primarily nodal.
- NHL can present as widespread (low grade) or localized extranodal (intermediate/high grade) disease.
- Recurrences for both HD and NHL are typically evident within two years post-treatment.
Conclusions:
- Histologic clues are critical for structuring efficient staging workups in NHL.
- Understanding HD's pattern of spread aids in selecting appropriate imaging for staging and follow-up.
- Differentiating treatment complications from recurrent disease is vital in post-treatment imaging.