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Commentary: Out with the new, in with the old: Evaluating the Ross procedure in patients aged >50 years

Ryan P Plichta1, Edward P Chen1

  • 1Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, NC.

The Journal of Thoracic and Cardiovascular Surgery
|December 5, 2020
PubMed
Abstract

No abstract available in PubMed .

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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