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Cell-based immunotherapy in gynecologic malignancies
Kalika Kamat1, Venkatesh Krishnan, Jonathan S Berek
1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Women's Cancer Center, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA.
Purpose Of Review:
To provide an update on cell-based immunotherapies in solid tumors particularly in gynecological cancers.
Recent Findings:
Recent clinical trial results demonstrate safety and tolerability of different cell therapies in gynecological cancers. Novel approaches, such as harnessing the cells of the innate immune system are also under investigation in a phase I trial.
Summary:
Cell-based therapies are gaining widespread attention as evidenced by the increasing number of clinical trials encompassing both, innate and adaptive cells to target gynecological cancers. A majority of these therapeutic approaches are well tolerated and show promising results in early trials.
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