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Chronic recurrent multifocal osteomyelitis: diagnosis and treatment
Fernando Moreno-Mateo1, Sofía Hidalgo Perea2, Karen Brandt Onel3
1Orthopaedic Surgery Department, Hospital General de Villalba, Madrid, Spain.
Purpose Of Review:
The aim of this article is to review recent findings regarding the diagnosis and treatment of chronic recurrent multifocal osteomyelitis (CRMO).
Recent Findings:
An adequate understanding of pathophysiology along with the new advances in MRI imaging make it possible to determine the extent of disease and establish early treatment. TNF-α inhibitors and bisphosphonates have shown to be a well-tolerated and efficient treatment for CRMO providing both symptomatic relief and normalization of bone morphology.
Summary:
The results of recent studies suggest that a better knowledge of the genetic and molecular factors will allow early diagnosis and the development of more effective individualized treatments in the future.
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