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Updated: Nov 27, 2025

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
Biomarkers in acute respiratory distress syndrome
Matthieu Jabaudon1,2,3, Raiko Blondonnet1,2, Lorraine B Ware3,4
1Department of Perioperative Medicine, CHU Clermont-Ferrand.
Purpose Of Review:
This article provides an overview of protein biomarkers for acute respiratory distress syndrome (ARDS) and their potential use in future clinical trials.
Recent Findings:
The protein biomarkers studied as indices of biological processes involved in the pathogenesis of ARDS may have diagnostic and/or prognostic value. Recently, they also proved useful for identifying ARDS phenotypes and assessing heterogeneity of treatment effect in retrospective analyses of completed clinical trials.
Summary:
This article summarizes the current research on ARDS biomarkers and provides insights into how they should be integrated as prognostic and predictive enrichment tools in future clinical trials.
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