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Updated: Nov 27, 2025
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Clinical status and lung function 10 weeks after severe SARS-CoV-2 infection
Jelle Smet1, Dimitri Stylemans1, Shane Hanon1
1Respiratory Division, University Hospital UZ Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium.
Fifty-four percent of COVID-19 survivors experienced abnormal lung function ten weeks post-diagnosis. Critically ill patients showed higher rates of restrictive pulmonary impairment, but this was not linked to residual symptoms or imaging results.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Clinical outcomes after COVID-19 are not well-documented.
- Understanding long-term respiratory status is crucial for patient recovery.
Purpose of the Study:
- To assess residual symptoms, lung function, and chest CT findings in COVID-19 survivors.
- To identify factors associated with pulmonary impairment post-infection.
Main Methods:
- Cross-sectional study of 220 COVID-19 survivors.
- Evaluated symptoms, pulmonary function (TLC, TLCO), and chest CT scans ~10 weeks post-diagnosis.
- Statistical analysis compared subgroups based on clinical characteristics and outcomes.
Main Results:
- 54% of survivors had abnormal lung function, primarily restrictive impairment.
- Restrictive impairment correlated with longer hospital stay, ICU admission, and mechanical ventilation.
- No association found between pulmonary restriction and symptom scores or CT findings.
Conclusions:
- A significant portion of COVID-19 survivors exhibit persistent lung function abnormalities.
- Critical illness severity is a predictor of restrictive pulmonary impairment.
- Abnormal lung function post-COVID-19 may not correlate with residual symptoms or imaging findings.
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