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Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

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Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
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Spinal Nerves: Plexus II01:21

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The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
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Spinal Nerves: Plexus I01:22

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Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Herpes zoster in patients with sciatica.

Der-Shin Ke1, Chao-Yu Hsu1,2,3,4,5,6,7, Cheng-Li Lin8,9

  • 1Department of Medical Education, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi, Taiwan.

BMC Musculoskeletal Disorders
|December 6, 2020
PubMed
Summary
This summary is machine-generated.

Sciatica increases the risk of developing herpes zoster (HZ). This study found a higher incidence of HZ in sciatica patients, suggesting a need for increased awareness and potential vaccination, especially for those over 50.

Keywords:
DepressionHerpes zosterObesitySciatica

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Epidemiology

Background:

  • Herpes zoster (HZ) is linked to various diseases.
  • The relationship between sciatica and HZ development is not well understood.
  • This study investigates HZ occurrence in patients with sciatica.

Purpose of the Study:

  • To determine if sciatica is a risk factor for developing herpes zoster (HZ).
  • To evaluate the incidence of HZ in a cohort of patients diagnosed with sciatica.

Main Methods:

  • A cohort of 49,023 sciatica patients was established (2000-2012).
  • Patients were matched with 49,023 controls without sciatica based on age, sex, and index year.
  • Follow-up occurred until HZ diagnosis, insurance withdrawal, death, or end of 2013.

Main Results:

  • Sciatica patients exhibited a significantly higher risk of HZ (adjusted HR=1.19; 95% CI=1.12-1.25).
  • Female patients had a slightly higher likelihood of HZ development than males (adjusted HR=1.07; 95% CI=1.02-1.12).
  • Comorbidities did not alter the increased HZ risk associated with sciatica.

Conclusions:

  • Sciatica is identified as a risk factor that increases the likelihood of developing herpes zoster (HZ).
  • Physicians should consider HZ risk in patients with sciatica.
  • Herpes zoster vaccination should be recommended for sciatica patients, particularly those over 50.