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Updated: Nov 27, 2025
Noninvasive Electrocardiography in the Perinatal Mouse
Published on: June 12, 2020
Non-invasive cardiovascular assessment of pregnancy in healthy female cats
P G Blanco1, D O Arias2, N Re2
1Center of Reproductive Physiology and Imaging Diagnosis, Faculty of Veterinary Sciences, National University of La Plata, 60 y 118, La Plata CC 296 (B 1900 AVW), Argentina; CONICET, CCT La Plata, Calle 8 1467, La Plata CC 296 (B 1900 AVW), Argentina.
Introduction:
The aim of this study was to evaluate cardiac morphology, indices of systolic and diastolic function, systolic blood pressure (SBP), and uterine artery resistance index (RI) during normal feline pregnancy. ANIMALS; MATERIALS AND METHODS: Twenty domestic short-hair pregnant queens, weighing 2.4-3.9 kg. Animals were assessed by two-dimensional, M-mode, and Doppler echocardiography, non-invasive SBP measurement, and uterine Doppler ultrasound every 10 days from mating to parturition.
Results:
Interventricular septal thickness at end-diastole and end-systole, left ventricular internal dimension at end-diastole, left ventricular free wall thickness at end-diastole and end-systole, fractional shortening, stroke volume, cardiac output (CO), heart rate, and peak velocities of early and late diastolic transmitral flow increased during the second half of gestation, while SBP and RI decreased during the same period (p < 0.01).
Discussion And Conclusions:
Cardiac structure and function varied during normal pregnancy in these queens. Eccentric hypertrophy, increased indices of systolic function, and increased measurements of CO seem to be the consequences of the hemodynamic modifications occurring during pregnancy. The assessment of maternal cardiovascular function may prove a useful screening tool to detect pregnancy complications in feline species.
