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Primary tuberculosis of the graft masquerading pyogenic liver abscess in a pediatric liver recipient
Jagadeesh Menon1, Bhushan Miraje1, Kinisha Patel1
1Department of Pediatric Gastroenterology & Hepatology, Bharat Institute of Higher Education and Research, Chennai, India.
Insights
Primary tuberculosis (TB) of a liver graft, presenting as multiple abscesses, is a rare complication after liver transplant (LT). Early diagnosis and treatment of Mycobacterium tuberculosis (MTB) in a pediatric patient were lifesaving.
Area of Science:
- Pediatric Hepatology
- Transplant Infectious Diseases
- Microbiology
Background:
- Liver transplantation (LT) is a life-saving procedure for end-stage liver disease.
- Graft complications can arise post-transplant, requiring vigilant monitoring.
- Primary graft tuberculosis (TB) is an exceptionally rare complication.
Abstract:
Primary tuberculosis (TB) of the graft presenting as multiple liver abscesses is previously unreported. A 14-month-old male child in the early post liver transplant (LT) period presented with high-grade fever spikes and on evaluation was found to have multiple pyogenic liver abscesses (PLA) in the CT abdomen. His fever was not responding to intravenous antibiotics and liver biopsy was done which showed numerous acid fast bacilli. Genetic analysis confirmed the bacilli as Mycobacterium tuberculosis (MTB). Timely diagnosis and prompt introduction of antituberculosis therapy were lifesaving.
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