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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Updated: Nov 27, 2025

A Melanoma Patient-Derived Xenograft Model
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Ear melanoma: a four-case series.

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  • 1Hospital Universitário Cassiano Antônio de Moraes, Universidade Federal do Espírito Santo, Vitória, ES, Brazil.

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|December 7, 2020
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Routine ear examinations in dermatology are crucial for early detection of external ear melanoma. Prompt diagnosis and surgical treatment significantly improve patient survival rates for this rare cancer.

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • External ear melanoma is a rare malignancy.
  • Early diagnosis and treatment are critical for patient survival.

Observation:

  • Four clinical cases of external ear melanoma are presented.
  • Patients aged 60-81 with melanocytic lesions underwent physical and dermoscopic examination.
  • Lesions suggestive of melanoma were identified in the outer ear.

Findings:

  • Surgical excision was the primary treatment modality.
  • Histopathological studies confirmed melanoma diagnoses.
  • Early-stage diagnosis facilitated timely therapeutic intervention.

Implications:

  • Routine dermatological examination of the ears is vital for identifying potential melanomas.
  • Early detection and treatment positively impact overall survival in external ear melanoma patients.