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Multidisciplinary brain metastasis clinic: is it effective and worthwhile?
Annu Rajpurohit1, Nilendu Purandare2, Aliasgar Moiyadi3
1Department of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Mumbai 400012, India.
Ecancermedicalscience
|December 7, 2020
Summary
A specialized multidisciplinary brain metastasis clinic significantly impacts treatment decisions for complex cases. This review shows that expert opinions alter patient care plans, improving management strategies for brain metastases.
Area of Science:
- Neuro-oncology
- Clinical Decision Making
- Multidisciplinary Care
Background:
- Brain metastasis management is complex, requiring a multidisciplinary approach.
- A dedicated brain metastasis clinic (BMC) was established to address challenging cases.
- This study reviews the impact of the BMC on clinical treatment decisions.
Observation:
- Ninety-nine patients with brain metastasis were evaluated between April 2018 and June 2019.
- Lung cancer was the most common primary malignancy (79.8%).
- Molecular markers like EGFR TKI mutations (31.3%) and ALK rearrangements (17.2%) were noted.
Findings:
- Treatment plans were altered in 46.5% of cases following BMC review.
- Intent of treatment shifted from palliative to curative in 5% of patients.
- Significant changes were observed in radiation (37.4%), targeted therapy (22.9%), and chemotherapy (15.2%) recommendations.
Implications:
- Multidisciplinary clinics demonstrably influence treatment decisions for brain metastases.
- Specialized clinics can optimize patient management by integrating diverse expert opinions.
- This approach enhances the effectiveness of treatment strategies for complex neurological oncological conditions.
