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A Case of Vancomycin-induced Acute Generalized Exanthematous Pustulosis Confirmed by Patch Testing
Cory Pettit1, John Trinidad1, Benjamin Kaffenberger1
1All authors are with the Division of Dermatology at Ohio State University in Columbus, Ohio.
The Journal of Clinical and Aesthetic Dermatology
|December 7, 2020
Summary
Acute generalized exanthematous pustulosis (AGEP) is a rare skin reaction. This case study details a prolonged vancomycin-induced AGEP confirmed by patch testing.
Area of Science:
- Dermatology
- Pharmacology
- Clinical Medicine
Background:
- Acute generalized exanthematous pustulosis (AGEP) is a rare, severe cutaneous adverse drug reaction.
- Characterized by sudden onset of widespread pustules, erythema, and edema.
- Typically linked to pristinamycin and aminopenicillins, with rare vancomycin associations.

