Interaction between iron and dihydromyricetin extracted from vine tea

Area of Science:

• Biochemistry
• Spectroscopy
• Nutritional Science

Background:

• Dihydromyricetin (DMY), a natural flavonoid from vine tea, is known for its antioxidant properties.
• Iron is an essential mineral, but its bioavailability and stability are influenced by various factors.
• Understanding the interaction between DMY and iron is crucial for potential applications in nutrition and medicine.

Purpose of the Study:

• To investigate the interaction between dihydromyricetin (DMY) and iron ions (Fe(II) and Fe(III)).
• To evaluate the effect of DMY on the stability and solubility of iron ions.
• To explore the potential of DMY in modulating iron speciation and bioavailability.

Main Methods:

• UV absorption spectroscopy was employed to study spectral changes upon interaction.
• Fluorescence quenching spectroscopy was utilized to assess binding and interaction dynamics.
• Experiments were conducted across a range of pH values (3.0, 5.0, and 7.0).

Main Results:

• Iron ions significantly altered the UV absorption spectra of DMY.
• Iron ions exhibited an enhanced fluorescence effect on DMY.
• DMY demonstrated the ability to prevent Fe(II) oxidation and increase Fe(III) solubility.

Conclusions:

• DMY interacts with both Fe(II) and Fe(III) ions, influencing their spectral properties.
• DMY plays a protective role for Fe(II) and enhances the solubility of Fe(III).
• These findings suggest DMY's potential as a modulator of iron status and bioavailability.