Related Experiment Video
Updated: Nov 27, 2025

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
Published on: January 19, 2014
Scruples over Speckles
Benjamin Persons1, Eugene Y Kissin1
1Division of Rheumatology, Boston University Medical Center, Boston, MA, USA.
Abstract:
The "snowstorm" sign refers to the ultrasound appearance of motile hyperechoic specks within synovial fluid and has been reported to have a high specificity for gout. We describe three additional etiologies commonly encountered in the rheumatology clinic that can produce a snowstorm: calcium pyrophosphate deposition disease, fibrin collections/rice bodies, and gas bubbles in viscous synovial fluid.
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