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Related Experiment Video

Updated: Nov 27, 2025

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
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Neonatal Chikungunya: A case series.

Shyam S Meena1, Sugandha Arya2, Deepika Meena3

  • 1Associate Professor, Department of Pediatrics, VMMC & Safdarjung Hospital, New Delhi, India.

Tropical Doctor
|December 7, 2020
PubMed
Summary
This summary is machine-generated.

Chikungunya virus can transmit from mothers to neonates, causing symptoms like septicemia or meningitis. This study confirms vertical transmission and highlights severe clinical presentations in newborns.

Keywords:
Chikungunya virusfeverneonate

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Area of Science:

  • Virology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Chikungunya virus (CHIKV) is an RNA virus in the Togaviridae family, genus Alphavirus.
  • Transmitted by Aedes mosquitoes, CHIKV typically causes fever, arthralgia, and rash, usually self-limiting.
  • Vertical transmission of CHIKV from mother to neonate is a significant concern.

Observation:

  • A series of neonates diagnosed with Chikungunya virus infection was observed.
  • Enzyme-linked immunosorbent assay (ELISA) confirmed CHIKV infection in the neonates.
  • Clinical presentation in infected neonates mimicked septicemia or meningitis.

Findings:

  • Confirmed vertical transmission of Chikungunya virus from infected mothers to their neonates.
  • Documented severe clinical manifestations of CHIKV infection in newborns, including septicemia and meningitis.
  • Demonstrated the utility of ELISA for diagnosing CHIKV in neonatal cases.

Implications:

  • Highlights the risk of congenital Chikungunya virus infection and its potential severity.
  • Emphasizes the need for increased awareness and diagnostic vigilance for CHIKV in neonates, especially in endemic areas.
  • Suggests potential for improved management strategies for vertically infected newborns.