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Updated: Nov 27, 2025

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Vitamin D deficiency in children with bronchial asthma in southern Jordan: a cross-sectional study

Enas Al-Zayadneh1, Nedal Awad Alnawaiseh2, Salma Ajarmeh3

  • 1Department of Paediatrics, School of Medicine, The University of Jordan, Amman, Jordan.

The Journal of International Medical Research
|December 7, 2020
PubMed

Insights

Vitamin D deficiency is common in Jordanian children with asthma. Low vitamin D levels significantly correlate with increased asthma severity in pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Nutritional Biochemistry
  • Public Health

Background:

  • Bronchial asthma is a prevalent chronic respiratory condition in children.
  • Vitamin D deficiency is a growing global health concern with potential links to immune function and respiratory health.

Purpose of the Study:

  • To evaluate serum 25-hydroxyvitamin D (25-OH vitamin D) levels in Jordanian children diagnosed with bronchial asthma.
  • To investigate the relationship between 25-OH vitamin D status and asthma severity and control in this pediatric population.

Main Methods:

  • A cross-sectional study was conducted involving 98 children aged 1-14 years with asthma or recurrent wheezing.
  • Serum 25-OH vitamin D levels were measured.
  • Asthma severity and control were assessed using standardized criteria and questionnaires.

Main Results:

  • A high prevalence of vitamin D deficiency (41.8%) and insufficiency (34.7%) was observed among the studied children.
  • Only 23.5% of children had sufficient 25-OH vitamin D levels.
  • A significant correlation was identified between lower 25-OH vitamin D levels and increased asthma severity.

Conclusions:

  • Vitamin D deficiency is highly prevalent in Jordanian children suffering from bronchial asthma.
  • Low serum 25-OH vitamin D levels are significantly associated with greater asthma severity in this cohort.
Abstract

Keywords:
25-OH vitamin DAsthmaDeficiencyJordanPaediatrics

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