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Chancroid--a review.

C L Goh1

  • 1Middle Road Hospital, Singapore.

Annals of the Academy of Medicine, Singapore
|October 1, 1987
PubMed
Summary
This summary is machine-generated.

Chancroid, a tropical STI caused by Haemophilus ducreyi, presents diagnostic challenges due to polymicrobial ulcers. Antibiotic resistance varies geographically, impacting treatment efficacy.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Chancroid is a sexually transmitted infection (STI) primarily caused by the bacterium Haemophilus ducreyi.
  • The disease is more prevalent in tropical regions and presents diagnostic difficulties.
  • Clinical diagnosis is common, but ulcers are often polymicrobial, complicating treatment assessment.

Purpose of the Study:

  • To review the epidemiology, diagnosis, and management of chancroid.
  • To highlight the challenges in isolating Haemophilus ducreyi and diagnosing chancroid.
  • To discuss the impact of antibiotic resistance on treatment strategies.

Main Methods:

  • Literature review of epidemiology, diagnosis, and management of chancroid.
  • Analysis of in-vitro antibiotic resistance data for clinical isolates of Haemophilus ducreyi.

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  • Synthesis of information on diagnostic criteria and treatment guidelines.

    • Main Results:

    • Haemophilus ducreyi isolation is technically challenging.
    • Polymicrobial nature of chancroidal ulcers leads to varied antibiotic efficacy reports.
    • Significant geographic variation exists in antibiotic resistance patterns of Haemophilus ducreyi.

    Conclusions:

    • Accurate diagnosis of chancroid remains challenging.
    • Geographic variations in antibiotic resistance necessitate tailored treatment approaches.
    • Further research is needed to optimize management strategies for chancroid globally.